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史家岚(史家岚 哈尔滨医科大学)

史家岚,黑龙江省血液肿瘤研究所出凝血研究室主任,黑龙江省龙江学者,医学参考报血液病频道学术发展部主任,哈尔滨医科大学血液内科教授,博士生导师。国家自然科学基金课题评审专家;Blood, J Thrombosis and Haemostasis, Thrombosis and Haemostasis指定审稿人。

人物经历

1、 ?198301-198601:哈尔滨医科大学 ?基础医学系,助教

2、 ?198901-199101:哈尔滨医科大学 ?附属第一医院研究部,主管

3、 ?199101-199301:东京医科齿科大学 ?医学部,研究员

4、 ?199701-199801:东京医科齿科大学 ?医学部,讲师

5、 ?199801-200701:哈佛医学院 ?布里根医院血液肿瘤科,研究员,讲师

史家岚

6、 ?200701-:·哈尔滨医科大学 ?附属第一医院血液内科,教授,博士生导师

著述成果

成果论文

1、 ?Apoptosis of Neutrophils and Their Elimination by Kupffer Cell in Rat Liver.,Hepatology,1996; 24(5),第一作者

2、 ?Expression of P-selectin on hepatic endothelia and platelets promoting neutrophil removal by liver macrophages.,Blood,1998; 92(2),第一作者

3、 ?Evidence of hepatocyte apoptosis in rat liver after the administration of carbon tetrachloride.,Am J Pathol,1998; 153(2),第一作者

4、 ?Role of the liver in regulating numbers of circulating neutrophils.,Blood,2001; 98(4),第一作者

5、 ?Lactadherin inhibits enzyme complexes of blood coagulation by completing for phospholipid binding sites.,Blood,2003; 101(7),第一作者

6、 ?Lactadherin binds selectively to membranes containing phosphatidyl-L-serine and increased curvature.,Biochim Biophys Acta,2004; 1667(1),第一作者

7、 ?Lactadherin detects early phosphatidylserine exposure on immortalized leukemia cells undergoing programmed cell death.,Cytometry A,2006; 69(12),第一作者

8、 ?Platelet phosphatidylserine exposure during thrombosis is predominantly partial rather than complete:in vitro and in vivo detection utilizing lactadherin.,J Thromb Haemost,2008; 6(7),第一作者

9、 ?Procoagulant activity and phosphatidylserine of amniotic fluid cells.,Thromb Haemost,2009; 101(5),通讯作者

10、 ? Daunorubicin induces procoagulant activity of cultured endothelial cells through phosphatidylserine.,Thromb Haemost,2010;104(6),通讯作者

11、 ?Lactadherin functions as a probe for phosphatidylserine exposure and as an anticoagulant in the study of stored platelets.,Vox Sang,2011; 100(2),通讯作者

12、 ?Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells.,Blood,2012;119(10),通讯作者

13、 ?Homocysteine enhances clot-promoting activity of endothelial cells via phosphatidylserine externalization and microparticles formation.,Amino Acids,2012;43(3),通讯作者

14、 ? Effect of arsenic trioxide and daunorubicin on procoagulant activity of acute promyelocytic leukemia cells., Zhonghua Yi Xue Za Zhi,2012;92(16),通讯作者

15、 ?Procoagulant activity of erythrocytes and platelets through phosphatidylserine exposure and microparticles release in patients with nephrotic syndrome.,Thromb Haemost,2012;107(4),通讯作者

16、 ?Endothelial cell phagocytosis of senescent neutrophils decreases procoagulant activity.,Thromb Haemost,2013;109(6),通讯作者

17、 ?Role of erythrocytes and platelets in the prothrombotic status in polycythemia vera through phosphatidylserine exposure and microparticle generation.,Thromb Haemost,2013;109(6),并列一作

18、 ?Extracellular DNA traps released by acute promyelocytic leukemia cells through autophagy. ,Cell Death and Disease,2016;7(6),通讯作者

19、 ?Phosphotidylserine exposure and neutrophil extracellular traps enhance procoagulant activity in patients with inflammatory bowel disease.,Thromb Haemost,2016;115(4),通讯作者

20、 ?Promyelocytic extracellular chromatin exacerbates coagulation and fibrinolysis in acute promyelocytic leukemia.,Blood,2017;129(13),通讯作者

21、 ?Microparticles and blood cells induce procoagulant activity via phosphatidylserine exposure in NSTEMI patients following stent implantation.,International Journal of Cardiology,2016;223,通讯作者

22、 ?Enhanced Procoagulant Activity on Blood Cells after Acute Ischemic Stroke.,Translational stroke research,2017;8(1),通讯作者

23、 ?Phosphatidylserine on blood cells and endothelial cells contributes to the hypercoagulable state in cirrhosis.,Liver Int ,2016;36(12),通讯作者

24、 ?Circulating microparticles, blood cells and endothelium induce procoagulant activity in sepsis through phosphatidylserine exposure.,Shock,2016;45(3),通讯作者

25、 ?Procoagulant activity induced by transcatheter closure of atrial septal defects is associated with exposure of phosphatidylserine on microparticles, platelets and red blood cells.,Thrombosis research,2015;136(2),通讯作者

科研方向

主要研究方向: 白细胞及血小板生物学及其体内平衡 细胞成熟和凋亡过程细胞膜磷脂分析 乳粘素的功能和作用机制 APL凝血异常的分子病理 心血管疾病血栓形成机制。

荣誉记录

1、 ?体外LAK细胞杀伤人肺癌细胞的研究,黑龙江省科学技术进步奖,三等奖,199101。

总结史家岚(史家岚 哈尔滨医科大学)以下系列文章:

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